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Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells
The urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored protein that promotes tissue remodeling, tumor cell adhesion, migration and invasion. uPAR mediates degradation of the extracellular matrix through protease recruitment and enhances cell adhesion, migration and signaling...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576486/ https://ncbi.nlm.nih.gov/pubmed/28849762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23649 |
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