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DNA repair and sequence context affect (1)O(2)-induced mutagenesis in bacteria

Electronic excited molecular oxygen (singlet oxygen, (1)O(2)) is known to damage DNA, yielding mutations. In this work, the mutagenicity induced by (1)O(2) in a defined sequence of DNA was investigated after replication in Escherichia coli mutants deficient for nucleotide and base excision DNA repai...

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Bibliografiske detaljer
Main Authors: Agnez-Lima, L. F., Napolitano, R. L., Fuchs, R. P. P., Mascio, P. Di, Muotri, A. R., Menck, C. F. M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55764/
https://ncbi.nlm.nih.gov/pubmed/11433036
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