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DNA Sequence Context Affects UV-Induced Mutagenesis in Escherichia coli

We investigated the effect of altering the DNA sequence surrounding a mutable target site on the production of ultraviolet light (UV) induced mutations. Site-directed base substitutions were incorporated on both sides of a TAA sequence encoding a UAA nonsense defect in the tyrA14 allele of Escherich...

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Detalhes bibliográficos
Main Authors: Mak, Wai Bing, Fix, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276847/
https://ncbi.nlm.nih.gov/pubmed/18022648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2007.10.001
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