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Sequence Context Modulation of Polycyclic Aromatic Hydrocarbon-Induced Mutagenesis

DNA structural perturbations that are induced by site specifically and stereospecifically defined benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE) adducts are directly correlated with mutagenesis, leading to cellular transformation. Although previous investigations had established that replication...

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Detalhes bibliográficos
Main Authors: Chary, Parvathi, Stone, Michael P., Lloyd, R. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118935/
https://ncbi.nlm.nih.gov/pubmed/23913516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21806
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