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A targeted delivery strategy for the development of potent trypanocides
A new drug delivery strategy was investigated for the development of potent anti-parasitic compounds against Trypanosoma brucei, the causative agent of African sleeping sickness. Thus, potent in vitro hexokinase inhibitors were rendered cytotoxic by appending a tripeptide peroxosomal targeting seque...
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| Vydáno v: | Chem Commun (Camb) |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576345/ https://ncbi.nlm.nih.gov/pubmed/28726862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc03378h |
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