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A rectal cancer feasibility study with an embedded phase III trial design assessing magnetic resonance tumour regression grade (mrTRG) as a novel biomarker to stratify management by good and poor response to chemoradiotherapy (TRIGGER): study protocol for a randomised controlled trial

BACKGROUND: Pre-operative chemoradiotherapy (CRT) for MRI-defined, locally advanced rectal cancer is primarily intended to reduce local recurrence rates by downstaging tumours, enabling an improved likelihood of curative resection. However, in a subset of patients complete tumour regression occurs i...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রকাশিত:Trials
প্রধান লেখক: Battersby, Nick J., Dattani, Mit, Rao, Sheela, Cunningham, David, Tait, Diana, Adams, Richard, Moran, Brendan J., Khakoo, Shelize, Tekkis, Paris, Rasheed, Shahnawaz, Mirnezami, Alex, Quirke, Philip, West, Nicholas P., Nagtegaal, Iris, Chong, Irene, Sadanandam, Anguraj, Valeri, Nicola, Thomas, Karen, Frost, Michelle, Brown, Gina
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: BioMed Central 2017
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576102/
https://ncbi.nlm.nih.gov/pubmed/28851403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-2085-2
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