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Emerging functions of the Fanconi anemia pathway at a glance
Fanconi anemia (FA) is a rare disease, in which homozygous or compound heterozygous inactivating mutations in any of 21 genes lead to genomic instability, early-onset bone marrow failure and increased cancer risk. The FA pathway is essential for DNA damage response (DDR) to DNA interstrand crosslink...
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| Опубликовано в: : | J Cell Sci |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists Ltd
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576063/ https://ncbi.nlm.nih.gov/pubmed/28811338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.204909 |
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