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Emerging functions of the Fanconi anemia pathway at a glance

Fanconi anemia (FA) is a rare disease, in which homozygous or compound heterozygous inactivating mutations in any of 21 genes lead to genomic instability, early-onset bone marrow failure and increased cancer risk. The FA pathway is essential for DNA damage response (DDR) to DNA interstrand crosslink...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Sumpter, Rhea, Levine, Beth
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576063/
https://ncbi.nlm.nih.gov/pubmed/28811338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.204909
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