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Gene functioning and storage within a folded genome
In mammals, genomic DNA that is roughly 2 m long is folded to fit the size of the cell nucleus that has a diameter of about 10 μm. The folding of genomic DNA is mediated via assembly of DNA-protein complex, chromatin. In addition to the reduction of genomic DNA linear dimensions, the assembly of chr...
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| Publicado no: | Cell Mol Biol Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5575855/ https://ncbi.nlm.nih.gov/pubmed/28861108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-017-0050-4 |
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