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Gene functioning and storage within a folded genome

In mammals, genomic DNA that is roughly 2 m long is folded to fit the size of the cell nucleus that has a diameter of about 10 μm. The folding of genomic DNA is mediated via assembly of DNA-protein complex, chromatin. In addition to the reduction of genomic DNA linear dimensions, the assembly of chr...

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Dades bibliogràfiques
Publicat a:Cell Mol Biol Lett
Autors principals: Razin, Sergey V., Ulianov, Sergey V.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575855/
https://ncbi.nlm.nih.gov/pubmed/28861108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-017-0050-4
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