Overexpression of C-type Natriuretic Peptide in Endothelial Cells Protects against Insulin Resistance and Inflammation during Diet-induced Obesity

The endogenous peptide C-type natriuretic peptide (CNP) binds its receptor, guanylyl cyclase B (GCB), and is expressed by endothelial cells in diverse tissues. Because the endothelial cells of visceral adipose tissue have recently been reported to play a role in lipid metabolism and inflammation, we...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Bae, Cho-Rong, Hino, Jun, Hosoda, Hiroshi, Arai, Yuji, Son, Cheol, Makino, Hisashi, Tokudome, Takeshi, Tomita, Tsutomu, Kimura, Toru, Nojiri, Takashi, Hosoda, Kiminori, Miyazato, Mikiya, Kangawa, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574992/
https://ncbi.nlm.nih.gov/pubmed/28852070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10240-1
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