Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer’s Disease Mice and Wild-Type Littermates

Alzheimer’s disease (AD) is the most common neurodegenerative disease mainly caused by abnormal tau phosphorylation, amyloid β (Aβ) deposition and neuroinflammation. As an important environmental factor, hypoxia has been reported to aggravate AD via exacerbating Aβ and tau pathologies. However, the...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Zhang, Feng, Zhong, Rujia, Li, Song, Fu, Zhenfa, Cheng, Cheng, Cai, Huaibin, Le, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574879/
https://ncbi.nlm.nih.gov/pubmed/28890695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00282
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