α-Synuclein Negatively Regulates Nurr1 Expression Through NF-κB-Related Mechanism

The nuclear receptor-related 1 protein (Nurr1) is critical for the development and survival of midbrain dopamine neurons that are predominantly affected and progressively degenerated in Parkinson’s disease (PD). The expression level of Nurr1 has been proposed to be modulated by α-synuclein (α-SYN),...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Jia, Congcong, Qi, Hongqian, Cheng, Cheng, Wu, Xuefei, Yang, Zhaofei, Cai, Huaibin, Chen, Sheng, Le, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235291/
https://ncbi.nlm.nih.gov/pubmed/32477062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00064
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