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Sensitization of gastric cancer cells to alkylating agents by glaucocalyxin B via cell cycle arrest and enhanced cell death

Severe side effects are major problems with chemotherapy of gastric cancer (GC). These side effects can be reduced by using sensitizing agents in combination with therapeutic drugs. In this study, the low/nontoxic dosage of glaucocalyxin B (GLB) was used with other DNA linker agents mitomycin C (MMC...

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Détails bibliographiques
Publié dans:Drug Des Devel Ther
Auteurs principaux: Ur Rahman, Muhammad Saif, Zhang, Ling, Wu, Lingyan, Xie, Yuqiong, Li, Chunchun, Cao, Jiang
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574593/
https://ncbi.nlm.nih.gov/pubmed/28860714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S145719
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