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Cell cycle arrest and apoptotic cell death in cultured human gastric carcinoma cells mediated by arsenic trioxide

AIM: To investigate the effect of arsenic trioxide on human gastric cancer cell line MKN45 with respect to both cytotoxicity and induction of apoptosis in vitro. METHODS: MKN45 cells were treated with arsenic trioxide (As(2)O(3)) at the concentration of 1, 5, and 10 µmol/L, respectively, for three s...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Shao, Qin-Shu, Ye, Zai-Yuan, Ling, Zhi-Qiang, Ke, Jin-Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316002/
https://ncbi.nlm.nih.gov/pubmed/15948253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i22.3451
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