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Sensitization of gastric cancer cells to alkylating agents by glaucocalyxin B via cell cycle arrest and enhanced cell death

Severe side effects are major problems with chemotherapy of gastric cancer (GC). These side effects can be reduced by using sensitizing agents in combination with therapeutic drugs. In this study, the low/nontoxic dosage of glaucocalyxin B (GLB) was used with other DNA linker agents mitomycin C (MMC...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ur Rahman, Muhammad Saif, Zhang, Ling, Wu, Lingyan, Xie, Yuqiong, Li, Chunchun, Cao, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574593/
https://ncbi.nlm.nih.gov/pubmed/28860714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S145719
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