High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease

Polycystic kidney disease (PKD) is a prevalent disorder characterized by renal cysts that lead to kidney failure. Various signaling pathways have been targeted to stop disease progression, but most interventions still focus on alleviating PKD-associated symptoms. The mechanistic complexity of the di...

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Bibliographic Details
Published in:SLAS Discov
Main Authors: Booij, Tijmen H., Bange, Hester, Leonhard, Wouter N., Yan, Kuan, Fokkelman, Michiel, Kunnen, Steven J., Dauwerse, Johannes G., Qin, Yu, van de Water, Bob, van Westen, Gerard J. P., Peters, Dorien J. M., Price, Leo S.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574491/
https://ncbi.nlm.nih.gov/pubmed/28644734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217716056
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