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Variable Cyst Development in Autosomal Dominant Polycystic Kidney Disease: The Biologic Context
Patients with autosomal dominant polycystic kidney disease (ADPKD) typically carry a mutation in either the PKD1 or PKD2 gene, which leads to massive cyst formation in both kidneys. However, the large intrafamilial variation in the progression rate of ADPKD suggests involvement of additional factors...
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| Publicado en: | J Am Soc Nephrol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Nephrology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118495/ https://ncbi.nlm.nih.gov/pubmed/27493259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016040425 |
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