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Variable Cyst Development in Autosomal Dominant Polycystic Kidney Disease: The Biologic Context

Patients with autosomal dominant polycystic kidney disease (ADPKD) typically carry a mutation in either the PKD1 or PKD2 gene, which leads to massive cyst formation in both kidneys. However, the large intrafamilial variation in the progression rate of ADPKD suggests involvement of additional factors...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Leonhard, Wouter N., Happe, Hester, Peters, Dorien J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118495/
https://ncbi.nlm.nih.gov/pubmed/27493259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016040425
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