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Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis
11β-Hydroxysteroid dehydrogenase-1 (11β-HSD1) predominantly converts inert glucocorticoids into active forms, thereby contributing to intracellular glucocorticoid levels. 11β-HSD1 is dynamically regulated during inflammation, including in macrophages where it regulates phagocytic capacity. The resol...
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| Publicado no: | J Endocrinol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bioscientifica Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5574305/ https://ncbi.nlm.nih.gov/pubmed/28676523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-17-0223 |
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