Oligodeoxynucleotides covalently linked to intercalating dyes as base sequence-specific ligands. Influence of dye attachment site.

New molecules with high and specific affinity for nucleic acid base sequences have been synthesized. They involve an oligodeoxynucleotide covalently attached to an intercalating dye. Visible absorption spectroscopy and fluorescence have been used to investigate the binding of poly(rA) to octadeoxyth...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Asseline, U, Toulme, F, Thuong, N T, Delarue, M, Montenay-Garestier, T, Hélène, C
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1984
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6723628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb01887.x
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