Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

The role of the neurovascular niche in CNS myelin regeneration is incompletely understood. Here, we show that, upon demyelination, CNS-resident pericytes (PCs) proliferate, and parenchymal non-vessel-associated PC-like cells (PLCs) rapidly develop. During remyelination, mature oligodendrocytes were...

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Publicado en:Cell Rep
Autores principales: De La Fuente, Alerie Guzman, Lange, Simona, Silva, Maria Elena, Gonzalez, Ginez A., Tempfer, Herbert, van Wijngaarden, Peter, Zhao, Chao, Di Canio, Ludovica, Trost, Andrea, Bieler, Lara, Zaunmair, Pia, Rotheneichner, Peter, O’Sullivan, Anna, Couillard-Despres, Sebastien, Errea, Oihana, Mäe, Maarja A., Andrae, Johanna, He, Liqun, Keller, Annika, Bátiz, Luis F., Betsholtz, Christer, Aigner, Ludwig, Franklin, Robin J.M., Rivera, Francisco J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2017
Materias:
Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574064/
https://ncbi.nlm.nih.gov/pubmed/28834740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.007
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