Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

The role of the neurovascular niche in CNS myelin regeneration is incompletely understood. Here, we show that, upon demyelination, CNS-resident pericytes (PCs) proliferate, and parenchymal non-vessel-associated PC-like cells (PLCs) rapidly develop. During remyelination, mature oligodendrocytes were...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: De La Fuente, Alerie Guzman, Lange, Simona, Silva, Maria Elena, Gonzalez, Ginez A., Tempfer, Herbert, van Wijngaarden, Peter, Zhao, Chao, Di Canio, Ludovica, Trost, Andrea, Bieler, Lara, Zaunmair, Pia, Rotheneichner, Peter, O’Sullivan, Anna, Couillard-Despres, Sebastien, Errea, Oihana, Mäe, Maarja A., Andrae, Johanna, He, Liqun, Keller, Annika, Bátiz, Luis F., Betsholtz, Christer, Aigner, Ludwig, Franklin, Robin J.M., Rivera, Francisco J.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2017
Sujets:
Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574064/
https://ncbi.nlm.nih.gov/pubmed/28834740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.007
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