Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

The role of the neurovascular niche in CNS myelin regeneration is incompletely understood. Here, we show that, upon demyelination, CNS-resident pericytes (PCs) proliferate, and parenchymal non-vessel-associated PC-like cells (PLCs) rapidly develop. During remyelination, mature oligodendrocytes were...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: De La Fuente, Alerie Guzman, Lange, Simona, Silva, Maria Elena, Gonzalez, Ginez A., Tempfer, Herbert, van Wijngaarden, Peter, Zhao, Chao, Di Canio, Ludovica, Trost, Andrea, Bieler, Lara, Zaunmair, Pia, Rotheneichner, Peter, O’Sullivan, Anna, Couillard-Despres, Sebastien, Errea, Oihana, Mäe, Maarja A., Andrae, Johanna, He, Liqun, Keller, Annika, Bátiz, Luis F., Betsholtz, Christer, Aigner, Ludwig, Franklin, Robin J.M., Rivera, Francisco J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2017
Ämnen:
Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574064/
https://ncbi.nlm.nih.gov/pubmed/28834740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.007
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