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Activatable clinical fluorophore-quencher antibody pairs as dual molecular probes for the enhanced specificity of image-guided surgery

The emergence of fluorescently labeled therapeutic antibodies has given rise to molecular probes for image-guided surgery. However, the extraneous interstitial presence of an unbound and nonspecifically accumulated probe gives rise to false-positive detection of tumor tissue and margins. Thus, the c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biomed Opt
Prif Awduron: Obaid, Girgis, Spring, Bryan Q., Bano, Shazia, Hasan, Tayyaba
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society of Photo-Optical Instrumentation Engineers 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574035/
https://ncbi.nlm.nih.gov/pubmed/28853247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.22.12.121607
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