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Activatable clinical fluorophore-quencher antibody pairs as dual molecular probes for the enhanced specificity of image-guided surgery
The emergence of fluorescently labeled therapeutic antibodies has given rise to molecular probes for image-guided surgery. However, the extraneous interstitial presence of an unbound and nonspecifically accumulated probe gives rise to false-positive detection of tumor tissue and margins. Thus, the c...
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| 發表在: | J Biomed Opt |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society of Photo-Optical Instrumentation Engineers
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5574035/ https://ncbi.nlm.nih.gov/pubmed/28853247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.22.12.121607 |
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