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Hsp90 inhibitors radicicol and geldanamycin have opposing effects on Leishmania Aha1-dependent proliferation

Hsp90 and its co-chaperones are essential for the medically important parasite Leishmania donovani, facilitating life cycle control and intracellular survival. Activity of Hsp90 is regulated by co-chaperones of the Aha1 and P23 families. In this paper, we studied the expression of L. donovani Aha1 i...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Bartsch, Katharina, Hombach-Barrigah, Antje, Clos, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573691/
https://ncbi.nlm.nih.gov/pubmed/28455612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0800-2
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