Ribosome Profiling Reveals HSP90 Inhibitor Effects on Stage-Specific Protein Synthesis in Leishmania donovani

The 90-kDa heat shock protein (HSP90) of eukaryotes is a highly abundant and essential chaperone required for the maturation of regulatory and signal proteins. In the protozoan parasite Leishmania donovani, causative agent of the fatal visceral leishmaniasis, HSP90 activity is essential for cell pro...

Full description

Saved in:
Bibliographic Details
Published in:mSystems
Main Authors: Bifeld, Eugenia, Lorenzen, Stephan, Bartsch, Katharina, Vasquez, Juan-José, Siegel, T. Nicolai, Clos, Joachim
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247020/
https://ncbi.nlm.nih.gov/pubmed/30505948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00214-18
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items