Plasma succinate is a predictor of mortality in critically injured patients

BACKGROUND: Trauma is the leading cause of mortality under the age of 40. Recent observations on metabolic reprogramming during hypoxia and ischemia indicate that hypoxic mitochondrial uncoupling promotes the generation of succinate, which in turn mediates reperfusion injury and inflammatory sequela...

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Publié dans:J Trauma Acute Care Surg
Auteurs principaux: D’ALESSANDRO, Angelo, MOORE, Hunter B., MOORE, Ernest E., REISZ, Julie A., WITHER, Matthew J., GHASABYAN, Arsen, CHANDLER, James, SILLIMAN, Christopher C., HANSEN, Kirk C., BANERJEE, Anirban
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573618/
https://ncbi.nlm.nih.gov/pubmed/28590356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001565
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