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Plasma succinate is a predictor of mortality in critically injured patients

BACKGROUND: Trauma is the leading cause of mortality under the age of 40. Recent observations on metabolic reprogramming during hypoxia and ischemia indicate that hypoxic mitochondrial uncoupling promotes the generation of succinate, which in turn mediates reperfusion injury and inflammatory sequela...

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Bibliografiske detaljer
Udgivet i:J Trauma Acute Care Surg
Main Authors: D’ALESSANDRO, Angelo, MOORE, Hunter B., MOORE, Ernest E., REISZ, Julie A., WITHER, Matthew J., GHASABYAN, Arsen, CHANDLER, James, SILLIMAN, Christopher C., HANSEN, Kirk C., BANERJEE, Anirban
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573618/
https://ncbi.nlm.nih.gov/pubmed/28590356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001565
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