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Plasma succinate is a predictor of mortality in critically injured patients
BACKGROUND: Trauma is the leading cause of mortality under the age of 40. Recent observations on metabolic reprogramming during hypoxia and ischemia indicate that hypoxic mitochondrial uncoupling promotes the generation of succinate, which in turn mediates reperfusion injury and inflammatory sequela...
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| Publicado no: | J Trauma Acute Care Surg |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573618/ https://ncbi.nlm.nih.gov/pubmed/28590356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001565 |
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