Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock

BACKGROUND: Metabolomic investigations have consistently reported succinate accumulation in plasma after critical injury. Succinate receptors have been identified on numerous tissues, and succinate has been directly implicated in post-ischemic inflammation, organ dysfunction, platelet activation and...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Trauma Acute Care Surg
Κύριοι συγγραφείς: Slaughter, Anne L., D’Alessandro, Angelo, Moore, Ernest E., Banerjee, Anirban, Silliman, Christopher C., Hansen, Kirk C., Reisz, Julie A., Fragoso, Miguel, Wither, Matthew J., Bacon, Anthony, Moore, Hunter B., Peltz, Erik D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2016
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121066/
https://ncbi.nlm.nih.gov/pubmed/27602903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001256
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