The cellular and molecular determinants of emphysematous destruction in COPD

The introduction of microCT has made it possible to show that the terminal bronchioles are narrowed and destroyed before the onset of emphysematous destruction in COPD. This report extends those observations to the cellular and molecular level in the centrilobular phenotype of emphysematous destruct...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Suzuki, Masaru, Sze, Marc A., Campbell, Joshua D., Brothers, John F., Lenburg, Marc E., McDonough, John E., Elliott, W. Mark, Cooper, Joel D., Spira, Avrum, Hogg, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573394/
https://ncbi.nlm.nih.gov/pubmed/28842670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10126-2
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