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The cellular and molecular determinants of emphysematous destruction in COPD

The introduction of microCT has made it possible to show that the terminal bronchioles are narrowed and destroyed before the onset of emphysematous destruction in COPD. This report extends those observations to the cellular and molecular level in the centrilobular phenotype of emphysematous destruct...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Suzuki, Masaru, Sze, Marc A., Campbell, Joshua D., Brothers, John F., Lenburg, Marc E., McDonough, John E., Elliott, W. Mark, Cooper, Joel D., Spira, Avrum, Hogg, James C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573394/
https://ncbi.nlm.nih.gov/pubmed/28842670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10126-2
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