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A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...

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Detalhes bibliográficos
Main Authors: Campbell, Joshua D, McDonough, John E, Zeskind, Julie E, Hackett, Tillie L, Pechkovsky, Dmitri V, Brandsma, Corry-Anke, Suzuki, Masaru, Gosselink, John V, Liu, Gang, Alekseyev, Yuriy O, Xiao, Ji, Zhang, Xiaohui, Hayashi, Shizu, Cooper, Joel D, Timens, Wim, Postma, Dirkje S, Knight, Darryl A, Lenburg, Marc E, Hogg, James C, Spira, Avrum
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064320/
https://ncbi.nlm.nih.gov/pubmed/22937864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm367
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