A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...

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Autors principals: Campbell, Joshua D, McDonough, John E, Zeskind, Julie E, Hackett, Tillie L, Pechkovsky, Dmitri V, Brandsma, Corry-Anke, Suzuki, Masaru, Gosselink, John V, Liu, Gang, Alekseyev, Yuriy O, Xiao, Ji, Zhang, Xiaohui, Hayashi, Shizu, Cooper, Joel D, Timens, Wim, Postma, Dirkje S, Knight, Darryl A, Lenburg, Marc E, Hogg, James C, Spira, Avrum
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064320/
https://ncbi.nlm.nih.gov/pubmed/22937864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm367
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