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A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...

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Hlavní autoři: Campbell, Joshua D, McDonough, John E, Zeskind, Julie E, Hackett, Tillie L, Pechkovsky, Dmitri V, Brandsma, Corry-Anke, Suzuki, Masaru, Gosselink, John V, Liu, Gang, Alekseyev, Yuriy O, Xiao, Ji, Zhang, Xiaohui, Hayashi, Shizu, Cooper, Joel D, Timens, Wim, Postma, Dirkje S, Knight, Darryl A, Lenburg, Marc E, Hogg, James C, Spira, Avrum
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064320/
https://ncbi.nlm.nih.gov/pubmed/22937864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm367
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