The Parkinson’s disease-associated GPR37 receptor interacts with striatal adenosine A(2A) receptor controlling its cell surface expression and function in vivo

G protein-coupled receptor 37 (GPR37) is an orphan receptor associated to Parkinson’s disease (PD) neuropathology. Here, we identified GPR37 as an inhibitor of adenosine A(2A) receptor (A(2A)R) cell surface expression and function in vivo. In addition, we showed that GPR37 and A(2A)R do oligomerize...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Morató, Xavier, Luján, Rafael, López-Cano, Marc, Gandía, Jorge, Stagljar, Igor, Watanabe, Masahiko, Cunha, Rodrigo A., Fernández-Dueñas, Víctor, Ciruela, Francisco
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573386/
https://ncbi.nlm.nih.gov/pubmed/28842709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10147-x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi