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Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1

Kinetochores link chromosomes to spindle microtubules and are essential for accurate chromosome segregation during cell division. Kinetochores assemble at the centromeric region of chromosomes as a multiprotein complex. However, the molecular mechanisms of kinetochore assembly have not yet been full...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Gangula, Narmadha Reddy, Maddika, Subbareddy
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572923/
https://ncbi.nlm.nih.gov/pubmed/28696259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782896
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