A carregar...
WD Repeat Protein WDR48 in Complex with Deubiquitinase USP12 Suppresses Akt-dependent Cell Survival Signaling by Stabilizing PH Domain Leucine-rich Repeat Protein Phosphatase 1 (PHLPP1)
PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) is a protein-serine/threonine phosphatase and a negative regulator of the PI3-kinase/Akt pathway. Although its function as a suppressor of tumor cell growth has been established, the mechanism of its regulation is not completely understood...
Na minha lista:
Main Authors: | , |
---|---|
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
|
Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843068/ https://ncbi.nlm.nih.gov/pubmed/24145035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503383 |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|