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Beclin-1 is required for chromosome congression and proper outer kinetochore assembly
The functions of Beclin-1 in macroautophagy, tumorigenesis and cytokinesis are thought to be mediated by its association with the PI3K-III complex. Here, we describe a new role for Beclin-1 in mitotic chromosome congression that is independent of the PI3K-III complex and its role in autophagy. Becli...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615652/ https://ncbi.nlm.nih.gov/pubmed/23478334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.23 |
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