Llwytho...

Beclin-1 is required for chromosome congression and proper outer kinetochore assembly

The functions of Beclin-1 in macroautophagy, tumorigenesis and cytokinesis are thought to be mediated by its association with the PI3K-III complex. Here, we describe a new role for Beclin-1 in mitotic chromosome congression that is independent of the PI3K-III complex and its role in autophagy. Becli...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Frémont, Stéphane, Gérard, Annabelle, Galloux, Marie, Janvier, Katy, Karess, Roger E, Berlioz-Torrent, Clarisse
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: European Molecular Biology Organization 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615652/
https://ncbi.nlm.nih.gov/pubmed/23478334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.23
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