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MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D(3) in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis

1,25-dihydroxyvitamin D3 (1,25D) used to treat human acute myeloid leukemia (AML) cells induces features of normal monocytes, but the mechanisms underlying this response is not fully understood. We hypothesized that one or more microRNAs (miRNAs) known to control mouse hematopoiesis and lineage comm...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Gocek, Elzbieta, Wang, Xuening, Liu, Xiuping, Liu, Chang-Gong, Studzinski, George P.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572464/
https://ncbi.nlm.nih.gov/pubmed/21816906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1717
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