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MicroRNAs181 regulate the expression of p27(Kip1) in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D(3)

Human myeloid leukemia cells exposed to 1,25-dihydroxyvitamin D(3) (1,25D), a major cancer chemopreventive agent, acquire features of normal monocytes and arrest in the G(1) phase of the cell cycle, due to the upregulation of p27(Kip1) and p21(Cip1), but the mechanism is not clear. Here evidence is...

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Detalhes bibliográficos
Main Authors: Wang, Xuening, Gocek, Elzbieta, Liu, Chang-Gong, Studzinski, George P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804747/
https://ncbi.nlm.nih.gov/pubmed/19221487
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