Characterization of a Francisella tularensis-Caenorhabditis elegans Pathosystem for the Evaluation of Therapeutic Compounds

Francisella tularensis is a highly infectious Gram-negative intracellular pathogen that causes tularemia. Because of its potential as a bioterrorism agent, there is a need for new therapeutic agents. We therefore developed a whole-animal Caenorhabditis elegans-F. tularensis pathosystem for high-thro...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jayamani, Elamparithi, Tharmalingam, Nagendran, Rajamuthiah, Rajmohan, Coleman, Jeffrey J., Kim, Wooseong, Okoli, Ikechukwu, Hernandez, Ana M., Lee, Kiho, Nau, Gerard J., Ausubel, Frederick M., Mylonakis, Eleftherios
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571314/
https://ncbi.nlm.nih.gov/pubmed/28652232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00310-17
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