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Activity of a novel protonophore against methicillin-resistant Staphylococcus aureus
AIM: Compound 1-(4-chlorophenyl)-4,4,4-trifluoro-3-hydroxy-2-buten-1-one (compound 1) was identified as a hit against methicillin-resistant Staphylococcus aureus (MRSA) strain MW2. METHODS & RESULTS: The MIC of compound 1 against MRSA was 4 μg/ml. The compound showed enhanced activity at acidic...
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| Publicado no: | Future Med Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Future Science Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5941710/ https://ncbi.nlm.nih.gov/pubmed/28771026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2017-0047 |
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