A Novel 6-Benzyl Ether Benzoxaborole Is Active against Mycobacterium tuberculosis In Vitro

We identified a novel 6-benzyl ether benzoxaborole with potent activity against Mycobacterium tuberculosis. The compound had an MIC of 2 μM in liquid medium. The compound was also able to prevent growth on solid medium at 0.8 μM and was active against intracellular bacteria (50% inhibitory concentra...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Patel, Nipul, O'Malley, Theresa, Zhang, Yong-Kang, Xia, Yi, Sunde, Bjorn, Flint, Lindsay, Korkegian, Aaron, Ioerger, Thomas R., Sacchettini, Jim, Alley, M. R. K., Parish, Tanya
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571309/
https://ncbi.nlm.nih.gov/pubmed/28674058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01205-17
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