Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors

The urokinase-type plasminogen activator receptor (uPAR) is a GPI-anchored cell membrane receptor that focuses urokinase (uPA) proteolytic activity on the cell surface. Its expression is increased in many human cancers, including non-small cell lung cancer (NSCLC) and colorectal cancer (CRC), and co...

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Vydáno v:Sci Rep
Hlavní autoři: Mauro, Concetta Di, Pesapane, Ada, Formisano, Luigi, Rosa, Roberta, D’Amato, Valentina, Ciciola, Paola, Servetto, Alberto, Marciano, Roberta, Orsini, Roberta Clara, Monteleone, Francesca, Zambrano, Nicola, Fontanini, Gabriella, Servadio, Adele, Pignataro, Giuseppe, Grumetto, Lucia, Lavecchia, Antonio, Bruzzese, Dario, Iaccarino, Antonino, Troncone, Giancarlo, Veneziani, Bianca Maria, Montuori, Nunzia, Placido, Sabino De, Bianco, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571185/
https://ncbi.nlm.nih.gov/pubmed/28839232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10062-1
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