The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi

The causative agent of Lyme borreliosis, the spirochete Borrelia burgdorferi, has been shown to induce expression of the urokinase receptor (uPAR); however, the role of uPAR in the immune response against Borrelia has never been investigated. uPAR not only acts as a proteinase receptor, but can also...

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Autori principali: Hovius, Joppe W. R., Bijlsma, Maarten F., van der Windt, Gerritje J. W., Wiersinga, W. Joost, Boukens, Bastiaan J. D., Coumou, Jeroen, Oei, Anneke, de Beer, Regina, de Vos, Alex F., Veer, Cornelis van 't, van Dam, Alje P., Wang, Penghua, Fikrig, Erol, Levi, Marcel M., Roelofs, Joris J. T. H., van der Poll, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678258/
https://ncbi.nlm.nih.gov/pubmed/19461880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000447
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