The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi

The causative agent of Lyme borreliosis, the spirochete Borrelia burgdorferi, has been shown to induce expression of the urokinase receptor (uPAR); however, the role of uPAR in the immune response against Borrelia has never been investigated. uPAR not only acts as a proteinase receptor, but can also...

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Autores principales: Hovius, Joppe W. R., Bijlsma, Maarten F., van der Windt, Gerritje J. W., Wiersinga, W. Joost, Boukens, Bastiaan J. D., Coumou, Jeroen, Oei, Anneke, de Beer, Regina, de Vos, Alex F., Veer, Cornelis van 't, van Dam, Alje P., Wang, Penghua, Fikrig, Erol, Levi, Marcel M., Roelofs, Joris J. T. H., van der Poll, Tom
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678258/
https://ncbi.nlm.nih.gov/pubmed/19461880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000447
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