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The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi

The causative agent of Lyme borreliosis, the spirochete Borrelia burgdorferi, has been shown to induce expression of the urokinase receptor (uPAR); however, the role of uPAR in the immune response against Borrelia has never been investigated. uPAR not only acts as a proteinase receptor, but can also...

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Hlavní autoři: Hovius, Joppe W. R., Bijlsma, Maarten F., van der Windt, Gerritje J. W., Wiersinga, W. Joost, Boukens, Bastiaan J. D., Coumou, Jeroen, Oei, Anneke, de Beer, Regina, de Vos, Alex F., Veer, Cornelis van 't, van Dam, Alje P., Wang, Penghua, Fikrig, Erol, Levi, Marcel M., Roelofs, Joris J. T. H., van der Poll, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678258/
https://ncbi.nlm.nih.gov/pubmed/19461880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000447
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