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Simple MD-based model for oxidative folding of peptides and proteins

Significant strides have been recently made to fold peptides and small proteins in silico using MD simulations. However, facilities are currently lacking to include disulfide bonding in the MD models of protein folding. To address this problem, we have developed a simple empirical protocol to model...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Izmailov, Sergei A., Podkorytov, Ivan S., Skrynnikov, Nikolai R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570944/
https://ncbi.nlm.nih.gov/pubmed/28839177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09229-7
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