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Structural and dynamic origins of ESR lineshapes in spin-labeled GB1 domain: the insights from spin dynamics simulations based on long MD trajectories

Site-directed spin labeling (SDSL) ESR is a valuable tool to probe protein systems that are not amenable to characterization by x-ray crystallography, NMR or EM. While general principles that govern the shape of SDSL ESR spectra are known, its precise relationship with protein structure and dynamics...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Izmailov, Sergei A., Rabdano, Sevastyan O., Hasanbasri, Zikri, Podkorytov, Ivan S., Saxena, Sunil, Skrynnikov, Nikolai R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976580/
https://ncbi.nlm.nih.gov/pubmed/31969574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56750-y
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