Lanean...

Origin of anti-tumor activity of the cysteine-containing GO peptides and further optimization of their cytotoxic properties

Antitumor GO peptides have been designed as dimerization inhibitors of prominent oncoprotein mucin 1. In this study we demonstrate that activity of GO peptides is independent of the level of cellular expression of mucin 1. Furthermore, these peptides prove to be broadly cytotoxic, causing cell death...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Tyuryaeva, Irina I., Lyublinskaya, Olga G., Podkorytov, Ivan S., Skrynnikov, Nikolai R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238392/
https://ncbi.nlm.nih.gov/pubmed/28091523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40217
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!