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Origin of anti-tumor activity of the cysteine-containing GO peptides and further optimization of their cytotoxic properties
Antitumor GO peptides have been designed as dimerization inhibitors of prominent oncoprotein mucin 1. In this study we demonstrate that activity of GO peptides is independent of the level of cellular expression of mucin 1. Furthermore, these peptides prove to be broadly cytotoxic, causing cell death...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5238392/ https://ncbi.nlm.nih.gov/pubmed/28091523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40217 |
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