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Unusual fragmentation of derivatized cysteine-containing peptides

RATIONALE: Modification of cysteines by aminoethylation results in side chains similar to those of lysine. Trypsin cleaves at this modified residue and this labeling method can facilitate the analysis of proteins, specifically antibodies. In this work, the ability to identify peptides containing ami...

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Bibliographic Details
Published in:Rapid Commun Mass Spectrom
Main Authors: DeGraan-Weber, Nick, Zhao, Bingqing, Reilly, James P.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430700/
https://ncbi.nlm.nih.gov/pubmed/29874404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.8196
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